Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095272 | 0.80 | NPY5R (0.35) | NPY5RKCNH2 | |
| SCHEMBL17604615 | 0.72 | NPY5R (0.44) | NPY5RKCNH2MAPK14 | |
| SCHEMBL16095192 | 0.70 | MGLL (0.38) | NPY5RKCNH2 | |
| SCHEMBL16094450 | 0.70 | NPY5R (0.34) | NPY5RKCNH2 | |
| SCHEMBL16033875 | 0.69 | NPY5R (0.38) | NPY5RKCNH2 | |
| SCHEMBL15104626 | 0.68 | NPY5R (0.53) | NPY5RKCNH2PPARGMAPK14 | |
| SCHEMBL16095604 | 0.67 | KDM4C (0.36) | NPY5RKCNH2 | |
| SCHEMBL17604548 | 0.66 | NPY5R (0.38) | NPY5RKCNH2 | |
| SCHEMBL16100476 | 0.65 | MAPK14 (0.41) | NPY5RKCNH2MAPK14 | |
| SCHEMBL16095455 | 0.64 | CYP19A1 (0.38) | NPY5RKCNH2CYP19A1MAPK14KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |