Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604614 | 0.82 | MAPK14 (0.46) | NPY5RKCNH2MAPK14GSK3B | |
| SCHEMBL16094913 | 0.79 | MAPK14 (0.39) | KDM4CMAPK14GSK3B | |
| SCHEMBL16095288 | 0.78 | KMT2A (0.43) | MAPK14GSK3B | |
| SCHEMBL16034033 | 0.77 | KDM4C (0.68) | KDM4C | |
| SCHEMBL16095454 | 0.75 | MAPK14 (0.41) | KDM4CNPY5RKCNH2MAPK14GSK3B | |
| SCHEMBL17604545 | 0.69 | NPY5R (0.37) | KDM4CNPY5RKCNH2USP30 | |
| SCHEMBL16095224 | 0.69 | MAPK14 (0.48) | NPY5RKCNH2MAPK14GSK3B | |
| SCHEMBL16094945 | 0.69 | KDM4C (0.51) | KDM4CMAPK14 | |
| SCHEMBL16095479 | 0.67 | KDM4C (0.65) | KDM4CMAPK14 | |
| SCHEMBL16094741 | 0.65 | MAPK14 (0.48) | NPY5RKCNH2MAPK14GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |