Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.48 |
| ▸ | GCGR | P47871 | 3/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094741 | 0.83 | MAPK14 (0.48) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL17604614 | 0.81 | MAPK14 (0.46) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL16095271 | 0.81 | NPY5R (0.34) | MAPK14NPY5RKCNH2 | |
| SCHEMBL16095914 | 0.80 | MAPK14 (0.50) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL16095105 | 0.80 | MAPK14 (0.46) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL16103402 | 0.77 | KDM4C (0.59) | — | |
| SCHEMBL15104626 | 0.72 | NPY5R (0.53) | MAPK14GCGRNPY5RKCNH2 | |
| SCHEMBL16095191 | 0.72 | MAPK14 (0.39) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL16095040 | 0.72 | NPY5R (0.36) | NPY5RKCNH2 | |
| SCHEMBL16095177 | 0.71 | KDM4C (0.39) | MAPK14GCGRMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |