SCHEMBL16095161

SCHEMBL16095161

CCC(CO)CC(CC)C(O)C(O)C(C)O

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.39
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28340607 0.85 TRPA1 (0.42) TRPA1ALDH1A1LMNATDP1TSHR
SCHEMBL4892118 0.82 TSHR (0.36) LMNATSHR
SCHEMBL4610776 0.73 TRPA1 (0.44) TRPA1ALDH1A1LMNATDP1TSHR
SCHEMBL4283257 0.72 LMNA (0.48) LMNATDP1TSHR
SCHEMBL27414879 0.72
SCHEMBL10786182 0.72 TRPA1 (0.47) TRPA1ALDH1A1LMNATDP1TSHR
SCHEMBL246160 0.71 ALDH1A1 (0.52) TRPA1ALDH1A1LMNATDP1TSHR
SCHEMBL602930 0.71 LMNA (0.65) TRPA1ALDH1A1LMNATSHR
SCHEMBL10263274 0.70 TRPA1 (0.45) TRPA1ALDH1A1LMNATDP1TSHR
SCHEMBL135878 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970571-A1 POLYESTER POLYOLS IMPARTING IMPROVED FLAMMABILITY PROPERTIES Stepan Company (US) 2016-01-20 EP disclosed
WO-2014150207-A1 POLYESTER POLYOLS IMPARTING IMPROVED FLAMMABILITY PROPERTIES STEPAN COMPANY (US) 2014-09-25 WO disclosed