Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095224 | 0.81 | MAPK14 (0.48) | NPY5RKCNH2MAPK14 | |
| SCHEMBL16094449 | 0.80 | USP30 (0.36) | NPY5RKCNH2MAPK14METAP2METAP1 | |
| SCHEMBL17604545 | 0.77 | NPY5R (0.37) | NPY5RKCNH2METAP2METAP1USP30 | |
| SCHEMBL16095040 | 0.76 | NPY5R (0.36) | NPY5RKCNH2METAP2METAP1USP30 | |
| SCHEMBL16095603 | 0.76 | LMNA (0.38) | MAPK14METAP2METAP1KDM4CTGFBR1 | |
| SCHEMBL16095836 | 0.75 | PHF8 (0.39) | MAPK14METAP2METAP1KDM4C | |
| SCHEMBL16034550 | 0.69 | KDM4C (0.39) | NPY5RKCNH2MAPK14KDM4CTGFBR1 | |
| SCHEMBL16033875 | 0.69 | NPY5R (0.38) | NPY5RKCNH2METAP2METAP1USP30 | |
| SCHEMBL9792784 | 0.66 | NPY5R (0.45) | NPY5RKCNH2METAP2METAP1USP30 | |
| SCHEMBL29500425 | 0.66 | NPY5R (0.45) | NPY5RKCNH2METAP2METAP1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |