Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095191 | 0.80 | MAPK14 (0.39) | MAPK14IDO1KDM1A | |
| SCHEMBL16094741 | 0.80 | MAPK14 (0.48) | MAPK14KCNH2NPY5RKDM1A | |
| SCHEMBL16095271 | 0.80 | NPY5R (0.34) | USP30METAP2METAP1MAPK14KCNH2 | |
| SCHEMBL16095484 | 0.77 | USP30 (0.38) | USP30METAP2METAP1KCNH2NPY5R | |
| SCHEMBL17604545 | 0.76 | NPY5R (0.37) | USP30METAP2METAP1KCNH2NPY5R | |
| SCHEMBL16095603 | 0.75 | LMNA (0.38) | METAP2METAP1MAPK14 | |
| SCHEMBL16095836 | 0.74 | PHF8 (0.39) | METAP2METAP1MAPK14 | |
| SCHEMBL16033744 | 0.70 | KDM4C (0.41) | USP30MAPK14KDM1A | |
| SCHEMBL16033875 | 0.68 | NPY5R (0.38) | USP30METAP2METAP1KCNH2NPY5R | |
| SCHEMBL29500425 | 0.66 | NPY5R (0.45) | USP30METAP2METAP1KCNH2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |