Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.60 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.45 |
| ▸ | GSK3B | P49841 | 5/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.41 |
| ▸ | KDM5A | P29375 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095792 | 0.82 | KDM4C (0.58) | KDM4CKDM2BKDM5BKDM5AKDM4A | |
| SCHEMBL16094991 | 0.80 | KDM4C (0.60) | KDM4CKDM2BKDM5BKDM5AKDM4A | |
| SCHEMBL16034003 | 0.75 | KDM4C (1.00) | KDM4CKDM2BKDM5BKDM5AKDM4A | |
| SCHEMBL20978714 | 0.72 | KDM4C (0.60) | KDM4CKDM2BKDM5BKDM5AKDM4A | |
| SCHEMBL16094974 | 0.72 | KDM4C (0.56) | KDM4CKDM2BMAPK14GSK3BKDM5B | |
| SCHEMBL16095505 | 0.72 | KDM4C (0.56) | KDM4CKDM2BMAPK14GSK3BKDM5B | |
| SCHEMBL16095596 | 0.72 | KDM4C (0.65) | KDM4CKDM2BMAPK14GSK3BKDM5B | |
| SCHEMBL16095313 | 0.70 | KDM4C (0.52) | KDM4CKDM2BKDM5BKDM5AKDM4A | |
| SCHEMBL28200273 | 0.68 | KDM2B (0.52) | KDM4CKDM2BMAPK14KDM5BKDM4B | |
| SCHEMBL23303939 | 0.66 | KMO (0.67) | KDM4CKDM2BKDM5BKDM5AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |