Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095270 | 0.84 | KDM4C (0.44) | NPY5RKCNH2KDM4CKCNK3CTSS | |
| SCHEMBL17604615 | 0.77 | NPY5R (0.44) | NPY5RKCNH2MAPK14 | |
| SCHEMBL16100476 | 0.74 | MAPK14 (0.41) | NPY5RKCNH2MAPK14 | |
| SCHEMBL16095353 | 0.74 | NPY5R (0.35) | NPY5RKCNH2KDM4CKCNK3HPGD | |
| SCHEMBL16102461 | 0.74 | KDM4C (0.42) | NPY5RKCNH2KDM4CMAPK14PHF8 | |
| SCHEMBL16095290 | 0.72 | DYRK1A (0.40) | KDM4CMAPK14 | |
| SCHEMBL16033756 | 0.72 | KDM4C (0.64) | KDM4CPHF8 | |
| SCHEMBL17604578 | 0.70 | KDM4C (0.40) | KCNH2KDM4CPHF8 | |
| SCHEMBL17604537 | 0.70 | KDM4C (0.40) | KCNH2KDM4CPHF8ALDH1A1HPGD | |
| SCHEMBL17604548 | 0.70 | NPY5R (0.38) | NPY5RKCNH2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |