Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102232 | 0.86 | RAB9A (0.44) | RAB9AKDM4EHKDC1HSP90AA1MAPT | |
| SCHEMBL17499517 | 0.85 | KDM4E (0.51) | RAB9AKDM4EHKDC1MAPTALDH1A1 | |
| SCHEMBL16096619 | 0.84 | RAB9A (0.37) | RAB9AKDM4EPDE10APLAUMAPT | |
| SCHEMBL17499219 | 0.83 | HKDC1 (0.36) | RAB9AKDM4EPLAUHKDC1HSP90AA1 | |
| SCHEMBL16096402 | 0.83 | KDM4E (0.46) | RAB9AKDM4EHKDC1HSP90AA1MAPT | |
| SCHEMBL22607505 | 0.83 | KDM4E (0.46) | RAB9AKDM4EHKDC1HSP90AA1MAPT | |
| SCHEMBL22607507 | 0.82 | KDM4E (0.45) | RAB9AKDM4EHKDC1HSP90AA1MAPT | |
| SCHEMBL17499188 | 0.82 | KDM4E (0.45) | RAB9AKDM4EHKDC1HSP90AA1MAPT | |
| SCHEMBL17499149 | 0.82 | ALDH1A1 (0.33) | RAB9AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL17499799 | 0.82 | KDM4E (0.33) | RAB9AKDM4EMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |