SCHEMBL17499149

SCHEMBL17499149

CC(=Nc1ccccc1O[Si](C)(C)C)c1cc(C)ncn1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499640 0.86 ALDH1A1 (0.45) ALDH1A1LMNAMAPTHSD17B10KDM4E
SCHEMBL17499490 0.83 ALDH1A1 (0.33) ALDH1A1LMNAMAPTHSD17B10KDM4E
SCHEMBL16097435 0.82 RAB9A (0.36) ALDH1A1LMNAMAPTHSD17B10KDM4E
SCHEMBL17499456 0.81 HKDC1 (0.35) ALDH1A1LMNAMAPTHSD17B10KDM4E
SCHEMBL17499485 0.80 KMT2A (0.36) ALDH1A1LMNAMAPTHSD17B10RAB9A
SCHEMBL17499517 0.79 KDM4E (0.51) ALDH1A1LMNAMAPTKDM4ERAB9A
SCHEMBL17499669 0.78 HSP90AA1 (0.41) ALDH1A1LMNAMAPTHSD17B10KDM4E
SCHEMBL17499699 0.78 ADRA2A (0.33) ALDH1A1LMNAMAPTHSD17B10KDM4E
SCHEMBL22607509 0.78 HSP90AA1 (0.41) ALDH1A1LMNAMAPTHSD17B10KDM4E
SCHEMBL17499257 0.76 GRM5 (0.38) ALDH1A1LMNAMAPTHSD17B10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed