Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NCF1 | P14598 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096504 | 0.83 | FFAR1 (0.36) | NCF1FFAR1THRAAPPMEN1 | |
| SCHEMBL16104939 | 0.79 | L3MBTL1 (0.36) | L3MBTL1NCF1FFAR1LMNATHRA | |
| SCHEMBL23264578 | 0.72 | NCF1 (0.42) | NCF1THRAAPPMEN1KMT2A | |
| SCHEMBL15219240 | 0.70 | NCF1 (0.49) | L3MBTL1NCF1LMNATHRAAPP | |
| SCHEMBL3631805 | 0.69 | NCF1 (0.41) | NCF1FFAR1LMNATHRAAPP | |
| SCHEMBL16098001 | 0.68 | FFAR1 (0.35) | L3MBTL1NCF1FFAR1THRAAPP | |
| SCHEMBL6344107 | 0.66 | L3MBTL1 (0.47) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2322205 | 0.65 | NQO1 (0.46) | L3MBTL1FFAR1KDM4EMEN1KMT2A | |
| SCHEMBL29957289 | 0.65 | NQO1 (0.46) | L3MBTL1FFAR1KDM4EMEN1KMT2A | |
| SCHEMBL3630920 | 0.65 | CA1 (0.48) | L3MBTL1NCF1LMNATHRAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970339-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | Eli Lilly and Company (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149793-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | ELI LILLY AND COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |