Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096504 | 0.82 | FFAR1 (0.36) | FFAR1NCF1TAAR1APPRARA | |
| SCHEMBL16104939 | 0.82 | L3MBTL1 (0.36) | FFAR1NCF1APPTHRAL3MBTL1 | |
| SCHEMBL5421640 | 0.76 | ADRB2 (0.32) | ADRB2 | |
| SCHEMBL5417502 | 0.73 | EED (0.36) | L3MBTL1 | |
| SCHEMBL15219240 | 0.72 | NCF1 (0.49) | NCF1TAAR1APPTHRATDP1 | |
| SCHEMBL5456962 | 0.71 | — | — | |
| SCHEMBL14268008 | 0.70 | NCF1 (0.37) | FFAR1NCF1TAAR1RARARARB | |
| SCHEMBL5421413 | 0.70 | HPGD (0.31) | L3MBTL1 | |
| SCHEMBL8259924 | 0.69 | NCF1 (0.49) | FFAR1NCF1TAAR1RARARARB | |
| SCHEMBL15295214 | 0.69 | ALDH1A1 (0.48) | NCF1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970339-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | Eli Lilly and Company (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149793-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | ELI LILLY AND COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |