Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | NCF1 | P14598 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097477 | 0.83 | L3MBTL1 (0.35) | FFAR1NCF1THRAAPPMEN1 | |
| SCHEMBL16098001 | 0.82 | FFAR1 (0.35) | FFAR1NCF1RARARARBTHRA | |
| SCHEMBL23264578 | 0.72 | NCF1 (0.42) | NCF1THRAAPPMEN1KMT2A | |
| SCHEMBL15219240 | 0.70 | NCF1 (0.49) | NCF1THRAAPPMEN1KMT2A | |
| SCHEMBL3631805 | 0.69 | NCF1 (0.41) | FFAR1NCF1THRAAPPMEN1 | |
| SCHEMBL14268008 | 0.68 | NCF1 (0.37) | FFAR1NCF1RARARARBTHRA | |
| SCHEMBL8259924 | 0.67 | NCF1 (0.49) | FFAR1NCF1RARARARBTHRA | |
| SCHEMBL17311319 | 0.67 | LMNA (0.32) | — | |
| SCHEMBL18418723 | 0.66 | KDM4E (0.41) | FFAR1RARARARBAPPTAAR1 | |
| SCHEMBL2556120 | 0.66 | L3MBTL1 (0.41) | NCF1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970339-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | Eli Lilly and Company (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149793-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | ELI LILLY AND COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |