Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.53 |
| ▸ | FABP3 | P05413 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472251 | 0.88 | FABP4 (0.56) | FABP4FABP5FABP3CYP1A2CYP2C19 | |
| SCHEMBL27098822 | 0.85 | MAOA (0.68) | FABP4FABP5FABP3CYP1A2CYP2C19 | |
| SCHEMBL28679845 | 0.81 | FABP4 (0.60) | FABP4FABP5FABP3CYP1A2CYP2C19 | |
| SCHEMBL9905075 | 0.79 | PSEN1 (0.50) | FABP4FABP5HDAC6HDAC1MAOA | |
| SCHEMBL9768532 | 0.79 | CYP1A2 (0.70) | FABP4FABP5FABP3CYP1A2CYP2C19 | |
| SCHEMBL3561822 | 0.79 | CYP1A2 (0.52) | FABP4FABP5FABP3CYP1A2CYP2C19 | |
| SCHEMBL30800895 | 0.79 | CYP1A2 (0.52) | FABP4FABP5FABP3CYP1A2CYP2C19 | |
| SCHEMBL13456337 | 0.78 | CYP1A2 (0.56) | FABP4FABP5FABP3CYP1A2CYP2C19 | |
| SCHEMBL1401150 | 0.77 | SLC6A4 (0.58) | FABP4FABP5HDAC6HDAC1MAOA | |
| SCHEMBL4552481 | 0.75 | FABP4 (0.68) | FABP4FABP5FABP3CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003172-A | The amides containing carbazole, carbamates and ureas as cryptochrome regulator | 同步制药公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-109627205-A | The preparation method and applications of a kind of carbazyl Isopropanolamine derivatives | 贵州大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-106458891-B | Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators | 同步制药公司 | 2019-04-09 | — | — | CN | disclosed |
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2016-01-28 | — | — | US | disclosed |
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | AR, KLK3, BRDT | FABP4 3191/4885FABP5 2398/4885FABP3 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.