SCHEMBL3561822

SCHEMBL3561822

C=CCCn1c2ccccc2c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
CYP2C19 P33261 2/20 0.52
ALDH1A1 P00352 2/20 0.51
HPGD P15428 1/20 0.51
HTT P42858 1/20 0.51
FABP4 P15090 3/20 0.48
FABP5 Q01469 3/20 0.48
FABP3 P05413 1/20 0.48
KDM4E B2RXH2 1/20 0.47
CYP19A1 P11511 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
TSHR P16473 1/20 0.45
HDAC6 Q9UBN7 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
BACE1 P56817 2/20 0.44
MAOA P21397 4/20 0.43
MAOB P27338 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30800895 1.00 CYP1A2 (0.52) CYP1A2CYP2C19ALDH1A1HPGDHTT
SCHEMBL3257839 0.88 FABP4 (0.51) CYP1A2CYP2C19ALDH1A1HPGDHTT
SCHEMBL9044084 0.86 FABP4 (0.53) CYP1A2CYP2C19FABP4FABP5HDAC6
SCHEMBL11340330 0.85 MAOA (0.54) FABP4FABP5HDAC6MAOAMAOB
SCHEMBL9160144 0.85 MAOA (0.54) FABP4FABP5HDAC6MAOAMAOB
SCHEMBL9768532 0.79 CYP1A2 (0.70) CYP1A2CYP2C19FABP4FABP5FABP3
SCHEMBL16098656 0.79 FABP4 (0.53) CYP1A2CYP2C19FABP4FABP5FABP3
SCHEMBL146503 0.78 CYP1A2 (0.56) CYP1A2CYP2C19ALDH1A1HPGDHTT
SCHEMBL24404708 0.78 HPGD (0.37) CYP1A2ALDH1A1HPGDHTTKDM4E
SCHEMBL6232859 0.78 ALDH1A1 (0.43) ALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724706-B Method for rapidly converting aldehyde group into cyano group 中国科学院兰州化学物理研究所 2024-04-12 CN disclosed
CN-115724706-A Method for quickly converting aldehyde group into cyano group 中国科学院兰州化学物理研究所 2023-03-03 CN disclosed
US-7663301-B2 for use as robust red organic phosphors GENERAL ELECTRIC COMPANY (US) 2010-02-16 US disclosed
WO-2008021745-A2 HEPATITIS C VIRUS ENTRY INHIBITORS ITHERX PHARMACEUTICALS, INC. (US) 2008-02-21 WO disclosed
WO-2008021745-A2 HEPATITIS C VIRUS ENTRY INHIBITORS ITHERX PHARMACEUTICALS, INC. (US) 2008-02-21 WO disclosed
WO-2006076247-A2 PHOSPHORESCENT FLUORENE, ANTHRACENE AND/OR THIOPHENE SUBSTITUTED METALLO- PORPHYRINS AND RELATED COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2006-07-20 WO disclosed
US-20060152149-A1 Porphyrin compositions GENERAL ELECTRIC COMPANY (US) 2006-07-13 US disclosed
EP-0349982-B1 Volume phase type hologram film and photosensitive resin composition employed therefor CANON KK (JP) 1994-10-12 EP disclosed
US-5240795-A Volume phase type hologram film and photosensitive resin composition employed therefor CANON KABUSHIKI KAISHA (JP) 1993-08-31 US disclosed
EP-0349982-A2 Volume phase type hologram film and photosensitive resin composition employed therefor CANON KABUSHIKI KAISHA (JP) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060152149-A1 Porphyrin compositions ACP1, MMS19, MVD CYP1A2 2696/4885CYP2C19 463/4885ALDH1A1 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.