Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 6/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 6/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472251 | 0.87 | FABP4 (0.56) | FABP4FABP5MAOAMAOBHDAC1 | |
| SCHEMBL1401150 | 0.86 | SLC6A4 (0.58) | FABP4FABP5MAOAMAOBHDAC1 | |
| SCHEMBL16098656 | 0.79 | FABP4 (0.53) | FABP4FABP5MAOAMAOBHDAC1 | |
| SCHEMBL6338101 | 0.79 | MAOA (0.69) | FABP4FABP5MAOAMAOBHDAC1 | |
| SCHEMBL5658338 | 0.79 | MAOA (0.69) | FABP4FABP5MAOAMAOBHDAC1 | |
| SCHEMBL5181736 | 0.79 | MAOA (0.69) | FABP4FABP5MAOAMAOBHDAC1 | |
| SCHEMBL10063551 | 0.79 | MAOA (0.69) | FABP4FABP5MAOAMAOBHDAC1 | |
| SCHEMBL551644 | 0.79 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9976723 | 0.79 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9905344 | 0.79 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649073-A2 | PROCESS FOR THE PREPARATION OF SEMICONDUCTOR MATERIALS, COMPOUNDS AND THEIR USE | The University Of Manchester (GB) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076886-A2 | NOVEL PROCESS AND COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2012-06-14 | — | — | WO | disclosed |