Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250380 | 0.71 | HSD11B1 (0.78) | LSSKMT2AMEN1HSD11B1GAA | |
| SCHEMBL1720832 | 0.69 | ADORA2B (0.37) | ADORA2BKMT2AMEN1GAAMAPT | |
| SCHEMBL9901143 | 0.67 | ADORA2B (0.60) | ADORA2BADORA2AADORA3ADORA1 | |
| SCHEMBL17387706 | 0.66 | ADORA2B (1.00) | ADORA2BADORA2AADORA3ADORA1 | |
| SCHEMBL5251036 | 0.65 | MAPT (0.75) | LSSKMT2AMEN1HSD11B1LMNA | |
| SCHEMBL5250329 | 0.65 | MEN1 (0.85) | LSSKMT2AMEN1HSD11B1LMNA | |
| SCHEMBL5250449 | 0.65 | HSD11B1 (0.64) | LSSKMT2AMEN1HSD11B1LMNA | |
| SCHEMBL2963235 | 0.65 | ALDH1A1 (0.72) | LSSKMT2AMEN1HSD11B1LMNA | |
| SCHEMBL4049209 | 0.65 | HTR1A (0.44) | LSSKMT2AMEN1GAAMAPT | |
| SCHEMBL5327436 | 0.63 | HSD11B1 (0.65) | LSSKMT2AMEN1HSD11B1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153424-A1 | REDUCING DIABETES IN PATIENTS RECEIVING HMG-COA REDUCTASE INHIBITORS (STATINS) | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) | 2014-09-25 | — | — | WO | disclosed |