Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351807 | 0.86 | POLB (0.67) | MAPTPOLBPTGER4KDM4ELMNA | |
| SCHEMBL16099248 | 0.86 | POLB (0.51) | MAPTPOLBPTGER4KDM4ELMNA | |
| SCHEMBL16093698 | 0.82 | ALDH1A1 (0.58) | MAPTPOLBPTGER4KDM4ELMNA | |
| SCHEMBL16099079 | 0.76 | KDM4E (0.50) | MAPTPOLBPTGER4KDM4ELMNA | |
| SCHEMBL16099544 | 0.75 | ALDH1A1 (0.66) | MAPTPOLBKDM4ELMNACNR2 | |
| SCHEMBL4726731 | 0.74 | KMT2A (0.54) | MAPTPOLBPTGER4KDM4ELMNA | |
| SCHEMBL14839671 | 0.71 | PTGER4 (0.47) | MAPTPOLBPTGER4KDM4ELMNA | |
| SCHEMBL16100095 | 0.69 | CYP19A1 (0.42) | MAPTPOLBKDM4EKMT2ACYP19A1 | |
| SCHEMBL8181203 | 0.68 | SIGMAR1 (0.49) | MAPTPOLBKDM4EMAPK1ALDH1A1 | |
| SCHEMBL28407053 | 0.67 | POLB (0.47) | MAPTPOLBPTGER4KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |