Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | RORA | P35398 | 2/20 | 0.39 |
| ▸ | RORB | Q92753 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411029 | 0.84 | KDM4E (0.61) | KDM4EHPGDALDH1A1MAPTHTT | |
| SCHEMBL28326868 | 0.84 | KDM4E (0.61) | KDM4EHPGDALDH1A1MAPTHTT | |
| SCHEMBL16093698 | 0.84 | ALDH1A1 (0.58) | KDM4EHPGDALDH1A1MAPTHTT | |
| SCHEMBL16097572 | 0.83 | ALDH1A1 (0.44) | KDM4EHPGDALDH1A1MAPTHTT | |
| SCHEMBL16093752 | 0.83 | HPGD (0.44) | KDM4EHPGDALDH1A1MAPTHTT | |
| SCHEMBL16099757 | 0.81 | PTGER4 (0.54) | KDM4EHPGDALDH1A1MAPTHTT | |
| SCHEMBL16093634 | 0.79 | MAPT (0.53) | MAPTMEN1KMT2ALMNASIGMAR1 | |
| SCHEMBL11757062 | 0.77 | KDM4E (0.76) | KDM4EHPGDALDH1A1MAPTHTT | |
| SCHEMBL13264839 | 0.77 | KDM4E (0.53) | KDM4EHPGDALDH1A1MAPTHTT | |
| SCHEMBL7979590 | 0.75 | KDM4E (0.59) | KDM4EHPGDALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |