Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16093698 | 0.82 | ALDH1A1 (0.58) | PTGER4KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL16093752 | 0.81 | HPGD (0.44) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL16099561 | 0.81 | KDM4E (0.47) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL16097572 | 0.81 | ALDH1A1 (0.44) | KDM4EHSD17B10ALDH1A1MAPTHPGD | |
| SCHEMBL16093825 | 0.79 | PGR (0.41) | PTGER4ALDH1A1MAPTHPGDHTT | |
| SCHEMBL16093634 | 0.76 | MAPT (0.53) | MEN1KMT2AMAPTL3MBTL1CNR2 | |
| SCHEMBL16099756 | 0.76 | HPGD (0.55) | PTGER4MAOAMAOBKDM4EHSD17B10 | |
| SCHEMBL24525575 | 0.74 | P2RX4 (0.58) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL22087155 | 0.74 | MAOA (0.68) | PTGER4MAOAMAOBKDM4EHSD17B10 | |
| SCHEMBL22042200 | 0.74 | MAOA (0.68) | PTGER4MAOAMAOBKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |