Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TSPO | P30536 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556827 | 0.84 | MAPT (0.51) | ALDH1A1SMN1; SMN2PPARGPPARASIGMAR1 | |
| SCHEMBL1921148 | 0.84 | MAPT (0.51) | ALDH1A1SMN1; SMN2PPARGPPARASIGMAR1 | |
| SCHEMBL16093698 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL16099561 | 0.83 | KDM4E (0.47) | ALDH1A1SIGMAR1HPGDMAPTKDM4E | |
| SCHEMBL16093752 | 0.83 | HPGD (0.44) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL16099757 | 0.81 | PTGER4 (0.54) | ALDH1A1HPGDMAPTKDM4EHTT | |
| SCHEMBL16093634 | 0.79 | MAPT (0.53) | SIGMAR1MAPTLMNA | |
| SCHEMBL1921157 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2PPARGPPARASIGMAR1 | |
| SCHEMBL28228399 | 0.77 | MAPT (0.47) | SMN1; SMN2PPARGPPARASIGMAR1DNM1 | |
| SCHEMBL16099114 | 0.75 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |