Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610075 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL1609795 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL1609796 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL1609905 | 0.82 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL1609906 | 0.82 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL14321437 | 0.82 | ALDH1A1 (0.58) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL14321657 | 0.82 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2POLBCYP1A2 | |
| Cyanide SCHEMBL27958675 | 0.79 | SMN1; SMN2 (0.41) | KDM4EALDH1A1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL1609338 | 0.79 | BLM (0.42) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL1609337 | 0.79 | BLM (0.42) | KDM4EALDH1A1SMN1; SMN2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731403-A | Insecticidal isoxazolines | BAYER CROPSCIENCE AG | 2012-10-17 | — | — | CN | claimed |
| EP-2069338-B1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2012-11-28 | — | — | EP | disclosed |
| CN-102731403-A | Insecticidal isoxazolines | BAYER CROPSCIENCE AG | 2012-10-17 | — | — | CN | disclosed |
| CN-101522672-B | Insecticidal isoxazolines | BAYER CROPSCIENCE AG | 2012-07-18 | — | — | CN | disclosed |
| EP-2332937-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330106-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20100249191-A1 | N-Methyl benzamide derivatives | BAYER CROPSCIENCE SA (FR) | 2010-09-30 | — | — | US | disclosed |
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | HAX1, INA, CYCS | KDM4E 1969/4885ALDH1A1 683/4885SMN1; SMN2 3144/4885 |
| US-20100249191-A1 | N-Methyl benzamide derivatives | GNMT, SCN1A, INA | KDM4E 583/4885ALDH1A1 691/4885SMN1; SMN2 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.