SCHEMBL16101161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16117974	0.90	KMT2A (0.46)	KMT2AMEN1CYP3A4CYP2D6CYP2C9
	SCHEMBL16117972	0.88	KMT2A (0.44)	KMT2AMEN1CYP3A4CYP2D6CYP2C9
	SCHEMBL16822551	0.86	KMT2A (0.46)	KMT2AMEN1CYP3A4CYP2D6CYP2C9
	SCHEMBL16117985	0.86	KMT2A (0.46)	KMT2AMEN1CYP3A4CYP2D6CYP2C9
	SCHEMBL27402995	0.84	GPR119 (0.44)	KMT2AMEN1CYP3A4CYP2D6CYP2C9
	SCHEMBL30961634	0.84	GPR119 (0.44)	KMT2AMEN1CYP3A4CYP2D6CYP2C9
	SCHEMBL6840313	0.83	KMT2A (0.44)	KMT2AMEN1MGLLGPR119NPC1
	SCHEMBL3234860	0.82	ALDH1A1 (0.43)	KMT2AMEN1MGLLGPR119NPC1
	SCHEMBL694333	0.81	KMT2A (0.50)	KMT2AMEN1CYP3A4CYP2D6CYP2C9
	SCHEMBL5136397	0.78	KMT2A (0.46)	KMT2AMEN1CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.