Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961634 | 1.00 | GPR119 (0.44) | GPR119ATMALDH1A1NPC1MAPT | |
| SCHEMBL27402698 | 0.92 | GPR119 (0.44) | GPR119ATMALDH1A1NPC1MAPT | |
| SCHEMBL4270203 | 0.89 | GPR119 (0.46) | GPR119ATMALDH1A1NPC1MAPT | |
| SCHEMBL8239992 | 0.89 | CACNA1A (0.50) | GPR119ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL21831014 | 0.89 | MEN1 (0.47) | ATMALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL21831041 | 0.89 | ALDH1A1 (0.44) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL30961623 | 0.88 | MGLL (0.46) | GPR119USP30NR1H2NR1H3 | |
| SCHEMBL27403371 | 0.88 | CYP3A4 (0.39) | GPR119ATMUSP30MMP1MMP3 | |
| SCHEMBL16101161 | 0.84 | KMT2A (0.44) | GPR119ATMALDH1A1NPC1MAPT | |
| SCHEMBL30961635 | 0.83 | MGLL (0.39) | GPR119MEN1KMT2AUSP30CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024124287-A1 | COMPOUNDS FOR TREATING VIRAL INFECTION | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2024-06-20 | — | — | WO | disclosed |