SCHEMBL16101347

SCHEMBL16101347

Cc1nc(C(=Nc2ccccc2O[SiH](C)C)c2ccccc2)cn1C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16102128 0.87 TDP1 (0.39) TDP1
SCHEMBL17499543 0.85 TDP1 (0.31) TDP1ESR1ESR2
SCHEMBL17499692 0.84 TDP1 (0.32) TDP1
SCHEMBL16098690 0.81 GAA (0.31) TDP1
SCHEMBL17499292 0.80 HTT (0.33) TDP1ESR1ESR2
SCHEMBL17499229 0.79 TSHR (0.41)
SCHEMBL17499299 0.79 GRM5 (0.33) ESR1ESR2
SCHEMBL16102259 0.78 HPGDS (0.32)
SCHEMBL17499237 0.77 ALDH1A1 (0.43) ESR1ESR2
SCHEMBL16100921 0.77 ESR1 (0.30) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed
EP-2969593-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES Bridgestone Corporation (JP) 2016-01-20 EP disclosed
WO-2014149931-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORPORATION (JP) 2014-09-25 WO disclosed