Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101251 | 0.86 | TSHR (0.44) | TSHRKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL16101714 | 0.84 | TSHR (0.42) | TSHRKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL17499259 | 0.84 | TSHR (0.36) | TSHRKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL16098690 | 0.81 | GAA (0.31) | RAB9ATP53SMN1; SMN2GAA | |
| SCHEMBL17499237 | 0.79 | ALDH1A1 (0.43) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL16101347 | 0.79 | TDP1 (0.31) | — | |
| SCHEMBL16101305 | 0.79 | RAB9A (0.37) | KMT2ANPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL17499239 | 0.79 | RAB9A (0.46) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL17499566 | 0.78 | GAA (0.33) | RAB9ASMN1; SMN2GAA | |
| SCHEMBL16102259 | 0.77 | HPGDS (0.32) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |