Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598140 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| Hydrogen Peroxide SCHEMBL11434421 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL1611733 | 0.81 | NPC1 (0.45) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL8076390 | 0.80 | ABCB11 (0.46) | ALDH1A1TSHRCYP2C9TRPA1 | |
| SCHEMBL9339775 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL11602428 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL9345966 | 0.78 | ESR1 (0.34) | TRPA1 | |
| SCHEMBL190310 | 0.77 | ACHE (0.50) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL5490041 | 0.77 | ACHE (0.50) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL6327571 | 0.77 | ACHE (0.50) | ALDH1A1TSHRCYP2C9GAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102584829-A | Pyrazole and pyrazine diketone derivative and application thereof | UNIV SHANDONG | 2012-07-18 | — | — | CN | claimed |
| CN-101367819-B | 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof | UNIV SHANDONG | 2010-08-18 | — | — | CN | claimed |
| CN-101633675-A | Preparation and application of 5-substituent group-6-substituent phenyl-2-ferrocenyl pyrazolo [1, 5-a] pyrazine-4(5H)-ketone derivative | UNIV SHANDONG | 2010-01-27 | — | — | CN | claimed |
| CN-101367819-A | 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof | UNIV SHANDONG (CN) | 2009-02-18 | — | — | CN | claimed |
| US-6846953-B1 | Aromatic amides | WARNER LAMBERT COMPANY (US) | 2005-01-25 | — | — | US | claimed |
| EP-1178953-B1 | AROMATIC AMIDES | WARNER LAMBERT CO (US) | 2003-12-03 | — | — | EP | claimed |
| US-6030978-A | EXHIBIT FUNGICIDAL EFFECT OR GROWTH-INHIBITORY EFFECT AGAINST FUNGI INCLUDING CUTANEOUS FILAMENTOUS FUNGUS, SUCH AS EPIDERMOPHYTON, MICROSPORUM, TRICHOPHYTON, SPOROTHRIX SCHENCKII, ASPERGILLUS OR CANDIDA; NONTOXICITY; | HANWHA CORPORATION (KR) | 2000-02-29 | — | — | US | claimed |
| US-6008356-A | BRBERINE SALT DERIVATIVE IS REACTED WITH SODIUM TETRABORATE AND POTASSIUM CARBONATE IN ALCOHOL SOLVEANT TO FORM INTERMEDIATE, REACTING INTERMEDIATE WITH ALKYL SUBSTITUENT IN ACETONITRILE SOLVENT, OXIDIZING THE FORMED INTERMEDIATE | HANWHA CORPORATION (KR) | 1999-12-28 | — | — | US | claimed |
| CN-106488935-A | Novel transition metal compound, comprises its transition metal catalysts for olefin polymerization compositionss and the preparation method of the copolymer of the Alathon using it or ethylene and alhpa olefin | 沙特基础工业爱思开 NEXLENE 私人有限公司 | 2017-03-08 | — | — | CN | disclosed |
| US-8999221-B2 | Curable composition for imprints, patterning method and pattern | FUJIFILM CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20140121292-A1 | CURABLE COMPOSITION FOR IMPRINTS, PATTERNING METHOD AND PATTERN | FUJIFILM CORPORATION (JP) | 2014-05-01 | — | — | US | disclosed |
| US-20120214999-A1 | METAL COMPLEX, PYRIDYLPHOSPHINE COMPOUND, AND METHOD FOR PRODUCING ALKYL METHACRYLATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-23 | — | — | US | disclosed |
| EP-2487179-A1 | METAL COMPLEX, PYRIDYLPHOSPHINE COMPOUND, AND METHOD FOR PRODUCING ALKYL METHACRYLATE | Sumitomo Chemical Co., Ltd (JP) | 2012-08-15 | — | — | EP | disclosed |
| CN-102584829-A | Pyrazole and pyrazine diketone derivative and application thereof | UNIV SHANDONG | 2012-07-18 | — | — | CN | disclosed |
| US-5739345-A | HYPOGLYCEMIC AND ANTIDIABETIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| CN-1157288-A | Benzimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1997-08-20 | — | — | CN | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| EP-0745600-A1 | Benzimidazole derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5399589-A | Oxalyl hydrazide-hydroxamic acid derivatives, their preparation and their use as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |
| US-5032616-A | Plants | TRACOR, INC. | 1991-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214999-A1 | METAL COMPLEX, PYRIDYLPHOSPHINE COMPOUND, AND METHOD FOR PRODUCING ALKYL METHACRYLATE | AP1M1, MPHOSPH6, MACO1 | ALDH1A1 2811/4885TSHR 4468/4885CYP2C9 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.