SCHEMBL9345966

SCHEMBL9345966

[CH2]c1ccc(C(C)CCl)cc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
TRPA1 O75762 3/20 0.33
TAAR1 Q96RJ0 3/20 0.33
ACHE P22303 1/20 0.31
AOC3 Q16853 1/20 0.30
ADRB2 P07550 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536253 0.87 ESR1 (0.41) ESR1ESR2TRPA1TAAR1ACHE
SCHEMBL8076390 0.78 ABCB11 (0.46) ESR1ESR2TRPA1TAAR1ACHE
SCHEMBL18045114 0.78 ACHE (0.48) ESR1ESR2TAAR1ACHE
SCHEMBL1610174 0.78 ALDH1A1 (0.44) TRPA1
SCHEMBL1304417 0.76 ESR1 (0.43) ESR1ESR2TAAR1ACHE
SCHEMBL10281071 0.76 AOC3 (0.38) TRPA1ACHEAOC3
SCHEMBL11239990 0.76 ESR1 (0.59) ESR1ESR2TAAR1
SCHEMBL10857961 0.76 GRIA4 (0.43) ESR1ESR2TAAR1ACHEAOC3
SCHEMBL2467595 0.76 ALDH1A1 (0.46) ESR1ESR2TAAR1
SCHEMBL2736711 0.75 TAAR1 (0.58) TRPA1TAAR1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5294720-A Viricides THE DUPONT MERCK PHARMACEUTICAL CO. (US) 1994-03-15 US disclosed