Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095268 | 0.85 | KDM4C (0.45) | KDM4CMAPK14GRIN1GRIN2B | |
| SCHEMBL16102665 | 0.79 | KDM4C (0.68) | KDM4CGCGRMAPK14MAPK13MAPK12 | |
| SCHEMBL16033756 | 0.78 | KDM4C (0.64) | KDM4CPHF8 | |
| SCHEMBL17604614 | 0.77 | MAPK14 (0.46) | NPY5RKCNH2GCGRMAPK14MAPK13 | |
| SCHEMBL16102462 | 0.74 | NPY5R (0.38) | KDM4CNPY5RKCNH2MAPK14MAPK13 | |
| SCHEMBL17604576 | 0.72 | KDM4C (0.47) | KDM4CKCNH2MAPK14PHF8GRIN2B | |
| SCHEMBL16095288 | 0.71 | KMT2A (0.43) | GCGRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL17604535 | 0.71 | KDM4C (0.46) | KDM4CKCNH2MAPK14PHF8GRIN1 | |
| SCHEMBL16095596 | 0.70 | KDM4C (0.65) | KDM4CMAPK14PHF8 | |
| SCHEMBL16095454 | 0.69 | MAPK14 (0.41) | KDM4CNPY5RKCNH2GCGRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |