Sugi Predict

Sugi Predict / Compounds / SCHEMBL1610495

SCHEMBL1610495

SCHEMBL1610495

O=C(O)c1cnc2cc(Cl)ccc2c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.49
▸ CYP2D6 P10635 1/20 0.49
▸ ALDH1A1 P00352 5/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ HPGD P15428 3/20 0.46
▸ HSD17B10 Q99714 3/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ PKM P14618 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ TSHR P16473 2/20 0.44
▸ TP53 P04637 1/20 0.44
▸ CASP1 P29466 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ SRC P12931 1/20 0.44
▸ PRNP P04156 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30592903 1.00 CYP1A2 (0.49) CYP1A2CYP2D6ALDH1A1CYP3A4CA1
Hydrochloric Acid SCHEMBL11866946 0.98 CYP1A2 (0.48) CYP1A2CYP2D6ALDH1A1CYP3A4CA1
SCHEMBL11704085 0.89 ALDH1A1 (0.47) CYP1A2CYP2D6ALDH1A1CYP3A4HPGD
SCHEMBL11866937 0.87 ALDH1A1 (0.45) CYP1A2CYP2D6ALDH1A1CYP3A4HPGD
SCHEMBL6202230 0.87 ALDH1A1 (0.50) ALDH1A1CA1CA2HPGDHSD17B10
SCHEMBL21130452 0.86 CSF1R (0.46) CYP1A2CYP2D6ALDH1A1CYP3A4KDM4E
SCHEMBL1178728 0.85 ALDH1A1 (0.49) CYP1A2CYP2D6ALDH1A1CYP3A4CA1
SCHEMBL27903036 0.83 CA12 (0.44) ALDH1A1CA1CA2HPGDHSD17B10
SCHEMBL18283587 0.81 ALDH1A1 (0.48) CYP1A2CYP2D6ALDH1A1CYP3A4MEN1
SCHEMBL1617941 0.81 HSD17B10 (0.41) ALDH1A1HPGDHSD17B10KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118596675-A Root penetration-resistant asphalt waterproof coiled material and preparation method thereof 河北豫源防水材料有限公司 2024-09-06 — — CN claimed
CN-114456110-A Synthesis method of 7-chloro-4-hydroxyquinoline-3-carboxylic acid 重庆南松凯博生物制药有限公司 2022-05-10 — — CN claimed
CN-212375200-U High-efficiency 7-chloro-4-hydroxyquinoline-3-carboxylic acid synthesis device 重庆医药高等专科学校 2021-01-19 — — CN claimed
CN-111675653-A Preparation method and application of impurities of 4-aminoquinoline compound 珠海润都制药股份有限公司 2020-09-18 — — CN claimed
CN-111362872-A Synthetic method of 4, 7-dichloroquinoline 重庆医药高等专科学校 2020-07-03 — — CN claimed
US-20190315770-A1 COMPOSITION FOR HARDENING SOFT TISSUE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2019-10-17 — — US claimed
EP-3498717-A1 COMPOSITION FOR HARDENING SOFT TISSUE The Catholic University of Korea Industry-Academic Cooperation Foundation (KR) 2019-06-19 — — EP claimed
CN-109790179-A Composition for hardening soft tissue 加图立大学校产学协力团 2019-05-21 — — CN claimed
CN-106700949-A Multifunctional polishing paste and preparation method and usage method thereof 安徽雷萨重工机械有限公司 2017-05-24 — — CN claimed
CN-103626699-A Industrial preparation method of 4,7-dichloroquinoline WUHAN WUYAO PHARMACEUTICAL CO LTD 2014-03-12 — — CN claimed
EP-2205558-B1 SUBSTITUTED N-PHENYL-PYRROLIDINYLMETHYLPYRROLIDINE AMIDES AND THERAPEUTIC USE THEREOF AS HISTAMINE H3 RECEPTOR MODULATORS SANOFI SA (FR) 2012-07-25 — — EP claimed
US-8227504-B2 Substituted N-phenyl-pyrrolidinylmethylpyrrolidine amides and therapeutic use thereof SANOFI (FR) 2012-07-24 — — US claimed
EP-2205558-A1 SUBSTITUTED N-PHENYL-PYRROLIDINYLMETHYLPYRROLIDINE AMIDES AND THERAPEUTIC USE THEREOF AS HISTAMINE H3 RECEPTOR MODULATORS Sanofi-Aventis (FR) 2010-07-14 — — EP claimed
US-20100173898-A1 SUBSTITUTED N-PHENYL-PYRROLIDINYLMETHYLPYRROLIDINE AMIDES AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2010-07-08 — — US claimed
WO-2009052063-A1 SUBSTITUTED N-PHENYL-PYRROLIDINYLMETHYLPYRROLIDINE AMIDES AND THERAPEUTIC USE THEREOF AS HISTAMINE H3 RECEPTOR MODULATORS SANOFI-AVENTIS (FR) 2009-04-23 — — WO claimed
CN-1091102-C 7-chloro-4-oxo-quinoline and its preparation method and novel use as medicine SINO FOREIGN JOINT VENTURE MAO (CN) 2002-09-18 — — CN claimed
US-6362340-B1 HEATING 4-HYDROXYQUINOLINECARBOXYLIC ACID; CONTROLLING TEMPERATURE Chimie, Rhodia (FR) 2002-03-26 — — US claimed
CN-1329598-A Method for preparing 4-hydroquinolines and/or tautomeric compounds RHODIA CHIMIE SA (FR) 2002-01-02 — — CN claimed
US-20250346575-A1 ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-11-13 — — US disclosed
US-3992540-A ANALGESICS ROUSSEL-UCLAF (FR) 1976-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100173898-A1 SUBSTITUTED N-PHENYL-PYRROLIDINYLMETHYLPYRROLIDINE AMIDES AND THERAPEUTIC USE THEREOF HRH3, HRH4, CNR1 CYP1A2 839/4885CYP2D6 1277/4885ALDH1A1 804/4885
US-20190315770-A1 COMPOSITION FOR HARDENING SOFT TISSUE PNLIP, AMY2A, RNASE1 CYP1A2 4782/4885CYP2D6 4796/4885ALDH1A1 3262/4885
US-20250346575-A1 ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF CRBN, IDH1, IDH2 CYP1A2 3222/4885CYP2D6 4028/4885ALDH1A1 849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.