Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610657 | 1.00 | MAPT (0.43) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1610734 | 0.82 | BCHE (0.41) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1610739 | 0.82 | BCHE (0.41) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1611706 | 0.79 | F2 (0.36) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1611707 | 0.79 | F2 (0.36) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL25300424 | 0.78 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1609222 | 0.75 | SMN1; SMN2 (0.34) | ALDH1A1L3MBTL1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL1609221 | 0.75 | SMN1; SMN2 (0.34) | ALDH1A1L3MBTL1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL1609796 | 0.71 | ALDH1A1 (0.41) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1609795 | 0.71 | ALDH1A1 (0.41) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731403-A | Insecticidal isoxazolines | BAYER CROPSCIENCE AG | 2012-10-17 | — | — | CN | claimed |
| EP-2069338-B1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2012-11-28 | — | — | EP | disclosed |
| CN-102731403-A | Insecticidal isoxazolines | BAYER CROPSCIENCE AG | 2012-10-17 | — | — | CN | disclosed |
| CN-101522672-B | Insecticidal isoxazolines | BAYER CROPSCIENCE AG | 2012-07-18 | — | — | CN | disclosed |
| EP-2332937-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330106-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20100249191-A1 | N-Methyl benzamide derivatives | BAYER CROPSCIENCE SA (FR) | 2010-09-30 | — | — | US | disclosed |
| CN-101522672-A | Insecticidal isoxazolines | BAYER CROPSCIENCE AG (DE) | 2009-09-02 | — | — | CN | disclosed |
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | HAX1, INA, CYCS | MAPT 4845/4885ALDH1A1 683/4885LMNA 450/4885 |
| US-20100249191-A1 | N-Methyl benzamide derivatives | GNMT, SCN1A, INA | MAPT 4838/4885ALDH1A1 691/4885LMNA 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.