Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351745 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL3493236 | 0.81 | HPGDS (0.60) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL6852927 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL5025427 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL24194274 | 0.75 | SMN1; SMN2 (0.52) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL6385502 | 0.75 | SMN1; SMN2 (0.52) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL11315081 | 0.75 | KDM4E (0.57) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL27321802 | 0.74 | RAB9A (0.63) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL3496121 | 0.74 | MAPT (0.48) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL10172532 | 0.73 | HPGDS (0.60) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014159214-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. (US) | 2014-10-02 | — | — | WO | disclosed |