Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493236 | 0.87 | HPGDS (0.60) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL6852927 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL5317799 | 0.86 | TRPM8 (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL16112290 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL27518675 | 0.81 | AKT2 (0.59) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL27321802 | 0.79 | RAB9A (0.63) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL3496121 | 0.79 | MAPT (0.48) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL1753182 | 0.78 | HPGDS (0.60) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL10172532 | 0.78 | HPGDS (0.60) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL5330670 | 0.78 | HPGDS (0.56) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041322-A1 | m-Pyrazolylamido tetramisole derivatives, compositions thereof, processes for production of such compounds and compositions and their use in treating helminthiasis | BEECHAM GROUP PLC (GB) | 1981-12-09 | — | — | EP | disclosed |