Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1612060 | 0.83 | KCNJ1 (0.38) | KCNJ1ALDH1A1KCNH2KMT2AMEN1 | |
| SCHEMBL1612057 | 0.83 | KCNJ1 (0.38) | KCNJ1ALDH1A1KCNH2KMT2AMEN1 | |
| SCHEMBL5480877 | 0.78 | NOTUM (0.49) | KCNJ1ALDH1A1KCNH2KMT2AMEN1 | |
| SCHEMBL29792818 | 0.78 | NOTUM (0.49) | KCNJ1ALDH1A1KCNH2KMT2AMEN1 | |
| SCHEMBL1610377 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14321145 | 0.75 | ALOX5AP (0.36) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL19832891 | 0.75 | KDM4E (0.33) | ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL16122376 | 0.74 | KCNJ1 (0.45) | KCNJ1ALDH1A1KCNH2KMT2AMEN1 | |
| SCHEMBL6078473 | 0.74 | NOTUM (0.51) | KCNJ1ALDH1A1KCNH2KMT2AMEN1 | |
| SCHEMBL4926658 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069338-B1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2012-11-28 | — | — | EP | disclosed |
| EP-2332937-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330106-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20100249191-A1 | N-Methyl benzamide derivatives | BAYER CROPSCIENCE SA (FR) | 2010-09-30 | — | — | US | disclosed |
| WO-2009141096-A1 | SUBSTITUTED SPIRO-ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | HAX1, INA, CYCS | KCNJ1 205/4885ALDH1A1 683/4885KCNH2 72/4885 |
| US-20100249191-A1 | N-Methyl benzamide derivatives | GNMT, SCN1A, INA | KCNJ1 241/4885ALDH1A1 691/4885KCNH2 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.