SCHEMBL1611234

SCHEMBL1611234

[C]#CC(CCCC)c1ccccc1C

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
CA2 P00918 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP19A1 P11511 2/20 0.32
MC4R P32245 1/20 0.31
CNR2 P34972 1/20 0.30
ACP3 P15309 1/20 0.30
CYSLTR2 Q9NS75 1/20 0.30
CYSLTR1 Q9Y271 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1612270 0.95 ESR1 (0.36) ESR1ALDH1A1CYP19A1MC4RCNR2
SCHEMBL1612475 0.89 ESR1 (0.39) ESR1CYP3A4CYP19A1MC4RACP3
SCHEMBL1611050 0.87 PTGES (0.33) CYP3A4TSHR
SCHEMBL1612588 0.82 ADRA2A (0.32) CYP3A4CNR2MEN1KMT2ANPSR1
SCHEMBL1611729 0.82 ESR1 (0.42) ESR1ALDH1A1CYP3A4CYP19A1MC4R
SCHEMBL1612072 0.81 CYSLTR2 (0.33) CA2ALDH1A1CYP3A4CYSLTR2CYSLTR1
SCHEMBL1611265 0.80 PDE5A (0.32) ESR1ALDH1A1CNR2MEN1KMT2A
SCHEMBL1612811 0.80 PDE5A (0.34) CNR2LMNA
SCHEMBL1610297 0.79 ALDH1A1 (0.41) ALDH1A1KMT2A
SCHEMBL1612280 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110087034-A1 Organic Semiconductor Material SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-04-14 US disclosed
EP-2248818-A1 ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110087034-A1 Organic Semiconductor Material OR10J3, TST, OR51E2 ESR1 1107/4885CA2 3911/4885ALDH1A1 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.