Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 3/20 | 0.31 |
| ▸ | NOS1 | P29475 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713075 | 1.00 | NOS2 (0.33) | NOS2PTPN1SLC6A4SLC6A3PKM | |
| SCHEMBL1609934 | 0.92 | SLC6A3 (0.35) | NOS2PTPN1SLC6A3PKMNOS3 | |
| SCHEMBL1609935 | 0.92 | SLC6A3 (0.35) | NOS2PTPN1SLC6A3PKMNOS3 | |
| SCHEMBL1610318 | 0.91 | ALDH1A1 (0.33) | PTPN1 | |
| SCHEMBL1610320 | 0.91 | ALDH1A1 (0.33) | PTPN1 | |
| SCHEMBL12713074 | 0.90 | PDE10A (0.35) | PTPN1SLC6A3 | |
| SCHEMBL1610775 | 0.90 | PDE10A (0.35) | PTPN1SLC6A3 | |
| SCHEMBL1610312 | 0.90 | PDE10A (0.35) | PTPN1SLC6A3 | |
| SCHEMBL1610532 | 0.87 | POLB (0.31) | — | |
| SCHEMBL1610535 | 0.87 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | NOS2 203/4885PTPN1 366/4885SLC6A4 2264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.