SCHEMBL161148

SCHEMBL161148

CCc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.54
DPYD Q12882 1/20 0.48
GAA P10253 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
CYP19A1 P11511 1/20 0.48
TSHR P16473 1/20 0.48
THPO P40225 1/20 0.48
MTOR P42345 1/20 0.48
HTT P42858 1/20 0.48
HBB P68871 1/20 0.48
PMP22 Q01453 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156784 0.85 ATAD2 (0.48) ATAD2
SCHEMBL5800398 0.83
SCHEMBL4353311 0.83 DPYD (0.50) ATAD2DPYDGAAALDH1A1LMNA
SCHEMBL356483 0.81 TYMP (0.49) ATAD2
SCHEMBL4273200 0.80 ATAD2 (0.44) ATAD2ALDH1A1
SCHEMBL4356407 0.80 ATAD2 (0.44) ATAD2
SCHEMBL357910 0.80 TYMP (0.50) ATAD2
SCHEMBL15562232 0.80 KDM4E (0.45) ATAD2DPYDALDH1A1MAPT
SCHEMBL44459 0.79 GAA (0.52) ATAD2DPYDGAAALDH1A1LMNA
SCHEMBL5798297 0.79 DPYD (0.46) ATAD2DPYDGAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2760 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
CN-119431343-A M6A demethylase ALKBH1 small molecule inhibitor, synthesis method and application 河南大学 2025-02-14 CN claimed
CN-119095964-A Multi-tail and multi-cap mRNA and uses thereof 博德研究所 2024-12-06 CN claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
US-20220195497-A1 HYBRIDIZING all-LNA OLIGONUCLEOTIDES ROCHE DIAGNOSTICS OPERATIONS, INC. 2022-06-23 US claimed
EP-3980554-A1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2022-04-13 EP claimed
CN-113939599-A Hybrid all-LNA oligonucleotides 豪夫迈·罗氏有限公司 2022-01-14 CN claimed
WO-2020245377-A1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. HOFFMANN-LA ROCHE AG (CH) 2020-12-10 WO claimed
US-10260071-B2 CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity COLEY PHARMACEUTICAL GMBH (DE) 2019-04-16 US claimed
US-5128458-A 2',3'-dideoxy-4'-thioribonucleosides as antiviral agents SOUTHERN RESEARCH INSTITUTE (US) 1992-07-07 US claimed
US-5126506-A Deoxygenation at 3-position of furan ring BRISTOL-MYERS COMPANY (US) 1992-06-30 US claimed
EP-0482081-A1 ANTIVIRAL COMPOSITION. HARMENBERG JOHAN (SE) 1992-04-29 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
WO-1991016333-A1 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1991-10-31 WO claimed
WO-1991001137-A1 ANTIVIRAL COMPOSITION HARMENBERG JOHAN (SE) 1991-02-07 WO claimed
EP-0273169-A2 Novel antiviral agents SRI INTERNATIONAL (US) 1988-07-06 EP claimed
EP-0272446-A1 Novel antiviral agents SRI INTERNATIONAL (US) 1988-06-29 EP claimed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP claimed
WO-1984004748-A2 NOVEL ANTIVIRAL AGENTS 1984-12-06 WO claimed