SCHEMBL357910

SCHEMBL357910

CCCCCc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYMP P19971 4/20 0.50
HCAR2 Q8TDS4 2/20 0.48
ATAD2 Q6PL18 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6573665 0.98 TYMP (0.51) TYMPHCAR2ATAD2
SCHEMBL356483 0.94 TYMP (0.49) TYMPHCAR2ATAD2
SCHEMBL156784 0.86 ATAD2 (0.48) TYMPHCAR2ATAD2
SCHEMBL11343851 0.82 KMT2A (0.51) TYMPHCAR2
SCHEMBL4353311 0.82 DPYD (0.50) ATAD2
SCHEMBL7607239 0.81 GAA (0.46)
SCHEMBL7603360 0.81 ALDH1A1 (0.44)
SCHEMBL10735494 0.81 KMT2A (0.50) TYMPHCAR2
SCHEMBL7599533 0.80 ALDH1A1 (0.42)
SCHEMBL161148 0.80 ATAD2 (0.54) ATAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 578 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150211004-A1 RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-07-30 US claimed
EP-2838541-A1 RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES Agency For Science, Technology And Research (SG) 2015-02-25 EP claimed
WO-2013158046-A1 RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-10-24 WO claimed
US-12606814-B2 Oligonucleotide probes and uses thereof CARIS SCIENCE, INC. (US) 2026-04-21 US disclosed
US-20260078383-A1 RNA NANOSTRUCTURES AND METHODS OF MAKING AND USING RNA NANOSTRUCTURES UNIV ARIZONA STATE (US) 2026-03-19 US disclosed
US-12577627-B2 Selective detection of different dengue virus RNA serotypes using tandem toehold-mediated displacement reactions ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONE STATE UNIVERSITY (US) 2026-03-17 US disclosed
US-20260041702-A1 AGENTS THAT INHIBIT CCN LIGAND-INDUCED SIGNALLING FOR TREATING DISEASE TRIBUNE THERAPEUTICS AB (SE) 2026-02-12 US disclosed
EP-4683716-A1 DNA NANODEVICES FOR SPECIFIC AND EFFICIENT DELIVERY OF FUNCTIONAL PAYLOADS TO THE CYTOPLASM AND METHODS OF THEIR USE Arizona Board of Regents on behalf of Arizona State University (US) 2026-01-28 EP disclosed
EP-4680212-A1 ADAR1 INHIBITORS FOR TREATING CANCER Institute of Cancer Research Royal Cancer Hospital (GB) 2026-01-21 EP disclosed
US-20260014278-A1 HYBRID PEPTIDE DENDRIMER SYSTEMS AND EXTRAHEPATIC DELIVERY NUNTIUS THERAPEUTICS LTD (GB) 2026-01-15 US disclosed
US-20260002156-A1 MODULAR RNA DELIVERY PLATFORMS AND METHODS OF THEIR USE UNIV ARIZONA STATE (US) 2026-01-01 US disclosed
WO-2003068961-A2 METHOD TO MODIFY DIFFERENTIATION OF PLURIPOTENTIAL STEM CELLS AXORDIA LIMITED (GB) 2003-08-21 WO disclosed
WO-2003008573-A2 SILENCING OF GENE EXPRESSION BY SIRNA MILNER ANNE JOSEPHINE (GB) 2003-01-30 WO disclosed
WO-2003002592-A1 APTAMERS AND ANTIAPTAMERS UNISEARCH LIMITED (AU) 2003-01-09 WO disclosed
WO-1999010365-A2 5',5'-LINKED OLIGOMERS HAVING ANTI-THROMBIN ACTIVITY GILEAD SCIENCES, INC. (US) 1999-03-04 WO disclosed
US-5756291-A IDENTIFYING OLIGOMER SEQUENCES; QUALITATIVE ANALYSIS; ANALYSIS OF THROMBIN BY COMPLEXING GILEAD SCIENCES, INC. (US) 1998-05-26 US disclosed
WO-1996008559-A1 GLYCOSAMINOGLYCAN-DEGRADING ENZYME INHIBITION AND RESULTANT DISEASE THERAPIES CARDIAC CRC NOMINEES PTY. LTD. (AU) 1996-03-21 WO disclosed
EP-0572529-A1 APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING GILEAD SCIENCES, INC. (US) 1993-12-08 EP disclosed
WO-1992014842-A1 APTAMERS SPECIFIC FOR THROMBIN AND METHODS OF USE GILEAD SCIENCES, INC. (US) 1992-09-03 WO disclosed
WO-1992014843-A1 APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING GILEAD SCIENCES, INC. (US) 1992-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577627-B2 Selective detection of different dengue virus RNA serotypes using tandem toehold-mediated displacement reactions DDX41, DDX5, DDX6 TYMP 2886/4885HCAR2 4477/4885ATAD2 2051/4885
US-12606814-B2 Oligonucleotide probes and uses thereof CD63, FLT4, NCL TYMP 814/4885HCAR2 4659/4885ATAD2 2943/4885
US-20260041702-A1 AGENTS THAT INHIBIT CCN LIGAND-INDUCED SIGNALLING FOR TREATING DISEASE PKD2, CCNK, PKD1 TYMP 1238/4885HCAR2 3340/4885ATAD2 2099/4885
US-20260078383-A1 RNA NANOSTRUCTURES AND METHODS OF MAKING AND USING RNA NANOSTRUCTURES PDCD1, TIA1, NSUN2 TYMP 2547/4885HCAR2 1781/4885ATAD2 1001/4885
US-20260014278-A1 HYBRID PEPTIDE DENDRIMER SYSTEMS AND EXTRAHEPATIC DELIVERY CD47, CD2BP2, CD40LG TYMP 1157/4885HCAR2 2753/4885ATAD2 1957/4885
US-20260002156-A1 MODULAR RNA DELIVERY PLATFORMS AND METHODS OF THEIR USE ZFR, PHAX, MTREX TYMP 3399/4885HCAR2 4676/4885ATAD2 760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.