Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 11/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16115158 | 1.00 | TACR1 (0.41) | TACR1PPARGPPARAEPHX1CETP | |
| SCHEMBL17500978 | 1.00 | TACR1 (0.41) | TACR1PPARGPPARAEPHX1CETP | |
| SCHEMBL9049025 | 0.74 | TRPA1 (0.51) | PPARGPPARA | |
| SCHEMBL16115249 | 0.71 | CETP (0.45) | TACR1CETP | |
| SCHEMBL16115247 | 0.71 | CETP (0.45) | TACR1CETP | |
| SCHEMBL16115157 | 0.71 | PPARG (0.42) | TACR1PPARGPPARAEPHX1CACNA1F | |
| SCHEMBL16115159 | 0.71 | PPARG (0.42) | TACR1PPARGPPARAEPHX1CACNA1F | |
| SCHEMBL16115248 | 0.69 | CTSL (0.45) | TACR1PPARGPPARACACNA1FCACNA1D | |
| SCHEMBL1811694 | 0.68 | SLC6A2 (0.50) | EPHX1 | |
| SCHEMBL28914994 | 0.68 | SLC6A2 (0.50) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978761-A1 | NOVEL OXAZOLIDINONE DERIVATIVE AS CETP INHIBITOR, ITS PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dong-A ST Co., Ltd. (KR) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014157994-A1 | NOVEL OXAZOLIDINONE DERIVATIVE AS CETP INHIBITOR, ITS PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG-A ST CO.,LTD (KR) | 2014-10-02 | — | — | WO | disclosed |