Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 15/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16115157 | 1.00 | PPARG (0.42) | PPARGPPARAACP3TACR1CACNA1F | |
| SCHEMBL17500978 | 0.71 | TACR1 (0.41) | PPARGPPARATACR1CACNA1FCACNA1D | |
| SCHEMBL16115158 | 0.71 | TACR1 (0.41) | PPARGPPARATACR1CACNA1FCACNA1D | |
| SCHEMBL16115155 | 0.71 | TACR1 (0.41) | PPARGPPARATACR1CACNA1FCACNA1D | |
| SCHEMBL28937263 | 0.68 | MEN1 (0.42) | — | |
| SCHEMBL28764311 | 0.68 | SRR (0.45) | PPARGPPARAEPHX1 | |
| SCHEMBL1938155 | 0.68 | BACE1 (0.60) | — | |
| SCHEMBL1938153 | 0.68 | BACE1 (0.60) | — | |
| SCHEMBL16115248 | 0.68 | CTSL (0.45) | PPARGPPARATACR1CACNA1FCACNA1D | |
| SCHEMBL28703064 | 0.67 | MAOB (0.43) | PPARGPPARAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978761-A1 | NOVEL OXAZOLIDINONE DERIVATIVE AS CETP INHIBITOR, ITS PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dong-A ST Co., Ltd. (KR) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014157994-A1 | NOVEL OXAZOLIDINONE DERIVATIVE AS CETP INHIBITOR, ITS PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG-A ST CO.,LTD (KR) | 2014-10-02 | — | — | WO | disclosed |