Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25193722 | 0.77 | MMP2 (0.36) | CYP3A4CYP1A2MMP8LMNAALDH1A1 | |
| SCHEMBL9049038 | 0.75 | TRPA1 (0.45) | TRPA1TSHRSMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL2969422 | 0.75 | MAPT (0.48) | TSHRSMN1; SMN2HIF1ACYP1A2KMT2A | |
| SCHEMBL28914994 | 0.74 | SLC6A2 (0.50) | TSHRSLC6A2TAAR1CYP1A2 | |
| SCHEMBL28237997 | 0.74 | SLC6A2 (0.50) | TSHRSLC6A2TAAR1CYP1A2 | |
| SCHEMBL1811694 | 0.74 | SLC6A2 (0.50) | TSHRSLC6A2TAAR1CYP1A2 | |
| SCHEMBL104847 | 0.74 | TRPA1 (0.55) | TRPA1TSHRSLC6A2TAAR1CYP1A2 | |
| SCHEMBL16115155 | 0.74 | TACR1 (0.41) | PPARGPPARA | |
| SCHEMBL16115158 | 0.74 | TACR1 (0.41) | PPARGPPARA | |
| SCHEMBL17500978 | 0.74 | TACR1 (0.41) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385456-B1 | High surface hardness transparent resin and polymerizable monomer | MITSUI TOATSU CHEMICALS (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5084538-A | HIGH SURFACE HARDNESS TRANSPARENT RESIN PREPARED FROM A COMPOUND HAVING AT LEAST ONE ISOPROPENYL PHENYL GROUP | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-01-28 | — | — | US | disclosed |