Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | GJA1 | P17302 | 1/20 | 0.36 |
| ▸ | GJB2 | P29033 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.35 |
| ▸ | AMY2A | P04746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Simmondsin SCHEMBL24484258 | 1.00 | MAPT (0.39) | MAPTSYNJ2STAT3MEN1KMT2A | |
| Simmondsin SCHEMBL11411453 | 1.00 | MAPT (0.39) | MAPTSYNJ2STAT3MEN1KMT2A | |
| Simmondsin SCHEMBL11521057 | 1.00 | MAPT (0.39) | MAPTSYNJ2STAT3MEN1KMT2A | |
| Simmondsin SCHEMBL29466685 | 1.00 | MAPT (0.39) | MAPTSYNJ2STAT3MEN1KMT2A | |
| SCHEMBL26355780 | 0.87 | SYNJ2 (0.40) | SYNJ2STAT3MEN1KMT2APTPN1 | |
| SCHEMBL30615017 | 0.70 | PTPN1 (0.44) | MAPTSYNJ2MEN1KMT2APTPN1 | |
| SCHEMBL30089929 | 0.70 | PTPN1 (0.44) | MAPTSYNJ2MEN1KMT2APTPN1 | |
| SCHEMBL5791294 | 0.69 | MAPT (0.40) | MAPTSYNJ2STAT3MEN1KMT2A | |
| SCHEMBL13401880 | 0.69 | SYNJ2 (0.48) | MAPTSYNJ2MEN1KMT2APTPN1 | |
| SCHEMBL24737159 | 0.68 | MEN1 (0.45) | SYNJ2STAT3MEN1KMT2AGJA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120118751-A | Celastrus sibiricus and application thereof | 江苏农林职业技术学院 | 2025-06-10 | — | — | CN | claimed |
| CN-115868447-B | Reproduction management method for synchronous estrus-returning and timing insemination of young cattle | 新疆天澳牧业有限公司 | 2024-06-18 | — | — | CN | claimed |
| US-11406678-B2 | Simmondsin formulation | Raes, Stefaan (BE) | 2022-08-09 | — | — | US | claimed |
| EP-3452095-B1 | SIMMONDSIN FORMULATION | Van Den Driessche Herman (BE) | 2021-04-07 | — | — | EP | claimed |
| EP-3452095-A2 | SIMMONDSIN FORMULATION | Van den Driessche, Herman (BE) | 2019-03-13 | — | — | EP | claimed |
| US-20190070238-A1 | SIMMONDSIN FORMULATION | VAN DEN DRIESSCHE, HERMAN (BE) | 2019-03-07 | — | — | US | claimed |
| EP-3366306-A2 | USE OF SOME PEPTIDES IN DIAGNOSIS AND TREATMENT OF DIABETES, OBESITY AND METABOLIC DISEASES ASSOCIATED THERETO | Istanbul Universitesi Rektorlugu (TR) | 2018-08-29 | — | — | EP | claimed |
| EP-3351262-A1 | CURAGLUTIDE FOR IN TREATMENT OF PREDIABETES, DIABETES, OBESITY AND METABOLIC DISEASES ASSOCIATED THERETO | Istanbul Universitesi Rektorlugu (TR) | 2018-07-25 | — | — | EP | claimed |
| WO-2017191501-A2 | SIMMONDSIN FORMULATION | D'OOSTERLYNCK ANDRÉ (BE) | 2017-11-09 | — | — | WO | claimed |
| CN-107034142-A | Tailor-made oil is prepared in heterotroph microorganism | 泰拉瑞亚控股公司 | 2017-08-11 | — | — | CN | claimed |
| JP-2003500452-A | — | — | 2003-01-07 | — | — | JP | claimed |
| CN-1358458-A | Jojoba seed and its extract in use of fat prevention and banting | WANG YIHONG (CN) | 2002-07-17 | — | — | CN | claimed |
| EP-1183039-A1 | PHARMACEUTICAL PREPARATIONS OF BIOACTIVE SUBSTANCES EXTRACTED FROM NATURAL SOURCES | Armadillo Pharmaceuticals, Inc. (US) | 2002-03-06 | — | — | EP | claimed |
| US-6245364-B1 | FEEDING SIMMONDSIN | INTERNATIONAL FLORA TECHNOLOGIES, LTD. | 2001-06-12 | — | — | US | claimed |
| WO-2000072861-A1 | PHARMACEUTICAL PREPARATIONS OF BIOACTIVE SUBSTANCES EXTRACTED FROM NATURAL SOURCES | ARMADILLO PHARMACEUTICALS, INC. (US) | 2000-12-07 | — | — | WO | claimed |
| US-6007823-A | WATER EXTRACTION OF WATER SOLUBLE MATERIAL FROM DEFATTED JOJOBA SEED MEAL, DRYING TO SOLIDIFY EXTRACTS, SELECTIVE SOLVENT EXTRACTION OF SIMMONDSINS WITH ETHANOL LIQUID PHASE AND SEPARATING FROM SOLID PHASE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1999-12-28 | — | — | US | claimed |
| WO-1999062530-A1 | SIMMONDSIN CONCENTRATE FROM JOJOBA | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1999-12-09 | — | — | WO | claimed |
| CN-1235547-A | Antiherpetic pharmaceutical compositions containing acyclovir for topical applicators | RECORDATI CHEM PHARM (CH) | 1999-11-17 | — | — | CN | claimed |
| US-5962043-A | FEEDING A SMALL BUT SUFFICIENT AMOUNT OF SIMMONDSIN COMPONENT TO PROVIDE SIMMONDSIN WITHIN THE RANGE OF 0.1% BY WEIGHT OF SAID DOG FOOD DRY MATTER MIX TO ABOUT 1.5% BY WEIGHT OF SAID DOG FOOD DRY MATTER MIX. | SEAL ROCK TECHNOLOGIES INCORPORATED (US) | 1999-10-05 | — | — | US | claimed |
| US-4148928-A | Method for the extraction of undesirable and/or toxic glucosidic compound from vegetables | SNAMPROGETTI S.P.A. (IT) | 1979-04-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190070238-A1 | SIMMONDSIN FORMULATION | SPIN2B, SNCA, CHKB | MAPT 171/4885SYNJ2 1319/4885STAT3 452/4885 |
| US-11406678-B2 | Simmondsin formulation | SPIN2B, SNCA, CHKB | MAPT 171/4885SYNJ2 1319/4885STAT3 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.