Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | GJA1 | P17302 | 1/20 | 0.36 |
| ▸ | GJB2 | P29033 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.35 |
| ▸ | AMY2A | P04746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Simmondsin SCHEMBL11411453 | 1.00 | MAPT (0.39) | MAPTSYNJ2STAT3MEN1KMT2A | |
| Simmondsin SCHEMBL11521057 | 1.00 | MAPT (0.39) | MAPTSYNJ2STAT3MEN1KMT2A | |
| Simmondsin SCHEMBL161237 | 1.00 | MAPT (0.39) | MAPTSYNJ2STAT3MEN1KMT2A | |
| Simmondsin SCHEMBL29466685 | 1.00 | MAPT (0.39) | MAPTSYNJ2STAT3MEN1KMT2A | |
| SCHEMBL26355780 | 0.87 | SYNJ2 (0.40) | SYNJ2STAT3MEN1KMT2APTPN1 | |
| SCHEMBL30615017 | 0.70 | PTPN1 (0.44) | MAPTSYNJ2MEN1KMT2APTPN1 | |
| SCHEMBL30089929 | 0.70 | PTPN1 (0.44) | MAPTSYNJ2MEN1KMT2APTPN1 | |
| SCHEMBL5791294 | 0.69 | MAPT (0.40) | MAPTSYNJ2STAT3MEN1KMT2A | |
| SCHEMBL13401880 | 0.69 | SYNJ2 (0.48) | MAPTSYNJ2MEN1KMT2APTPN1 | |
| SCHEMBL24737159 | 0.68 | MEN1 (0.45) | SYNJ2STAT3MEN1KMT2AGJA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | CHORDA PHARMA, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | CHORDA PHARMA, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20220168259-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | CHORDA PHARMA, INC. | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | HCAR2, HCAR3, TRPV1 | MAPT 3270/4885SYNJ2 2213/4885STAT3 3696/4885 |
| US-20220168259-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | HCAR2, HCAR3, TRPV1 | MAPT 3270/4885SYNJ2 2213/4885STAT3 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.