Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30559 | 1.00 | NOD1 (0.58) | NOD1S1PR1S1PR3GRM8GRM6 | |
| SCHEMBL7781962 | 0.98 | NOD1 (0.60) | NOD1S1PR1S1PR3PLA2G2CGPR84 | |
| SCHEMBL9005575 | 0.98 | NOD1 (0.60) | NOD1S1PR1S1PR3PLA2G2CGPR84 | |
| SCHEMBL7780467 | 0.98 | NOD1 (0.60) | NOD1S1PR1S1PR3PLA2G2CGPR84 | |
| Hydrochloric Acid SCHEMBL23510798 | 0.98 | NOD1 (0.56) | NOD1S1PR1S1PR3GRM8GRM6 | |
| Hydrochloric Acid SCHEMBL23510799 | 0.98 | NOD1 (0.56) | NOD1S1PR1S1PR3GRM8GRM6 | |
| SCHEMBL5495191 | 0.98 | NOD1 (0.56) | NOD1S1PR1S1PR3GRM8GRM6 | |
| SCHEMBL1220169 | 0.98 | NOD1 (0.60) | NOD1S1PR1S1PR3PLA2G2CGPR84 | |
| SCHEMBL7781960 | 0.98 | NOD1 (0.60) | NOD1S1PR1S1PR3PLA2G2CGPR84 | |
| SCHEMBL7351269 | 0.98 | NOD1 (0.60) | NOD1S1PR1S1PR3PLA2G2CGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520195-B | Novel nucleoside phosphonate prodrugs | 勒芬天主教大学 | 2023-01-17 | — | — | CN | disclosed |
| EP-3600556-A1 | NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES | Katholieke Universiteit Leuven (BE) | 2020-02-05 | — | — | EP | disclosed |
| CN-110520195-A | Novel nucleoside phosphonate prodrugs | UNIV LEUVEN KATH | 2019-11-29 | — | — | CN | disclosed |
| WO-2018172416-A1 | NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-09-27 | — | — | WO | disclosed |
| US-9266820-B2 | Nitric oxide donor compounds | NICOX SCIENCE IRELAND (IE) | 2016-02-23 | — | — | US | disclosed |
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | NOD1 1456/4885S1PR1 1511/4885S1PR3 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.