Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | P2RY10 | O00398 | 3/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28004490 | 0.83 | NOS1 (0.34) | ALDH1A1 | |
| SCHEMBL2519906 | 0.81 | GAA (0.37) | TDP1MEN1KMT2A | |
| SCHEMBL13416978 | 0.81 | MAPT (0.32) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL8005990 | 0.80 | NOS1 (0.34) | — | |
| SCHEMBL29270950 | 0.80 | MAPT (0.51) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL3308937 | 0.79 | CA12 (0.32) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL28779653 | 0.78 | DGKA (0.46) | MAPTALDH1A1CYP3A4TSHRATM | |
| SCHEMBL5967210 | 0.78 | SLC1A2 (0.46) | — | |
| SCHEMBL7266730 | 0.78 | SLC1A2 (0.46) | — | |
| SCHEMBL2519909 | 0.77 | MEN1 (0.36) | TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | MAPT 2611/4885LMNA 4506/4885ALDH1A1 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.