Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1613261 | 1.00 | PNMT (0.55) | PNMTPTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL29241791 | 0.82 | PNMT (0.49) | PNMTDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL17186646 | 0.81 | PNMT (0.58) | PNMTDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL28426322 | 0.81 | PNMT (0.58) | PNMTDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL10774995 | 0.81 | PNMT (0.63) | PNMTDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL252161 | 0.78 | PNMT (0.62) | PNMTDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL123076 | 0.78 | PNMT (0.62) | PNMTDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL5140756 | 0.75 | PNMT (0.51) | PNMTDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL4989855 | 0.75 | PNMT (0.68) | PNMTDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL5366733 | 0.75 | PNMT (0.72) | PNMTDRD2DRD4DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130017582-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2013-01-17 | — | — | US | disclosed |
| US-20110086397-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2011-04-14 | — | — | US | disclosed |
| US-7264951-B1 | Enhanced production of taxol and taxanes by cell cultures of Taxus species | PHYTON, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| EP-0954596-B1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON INC (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1538214-A1 | Enhanced production of taxanes by cell cultures of taxus species | PHYTON, INC. (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-1398384-A1 | Enhanced production of taxanes by cell cultures of taxus species | Phyton Inc. (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | disclosed |