SCHEMBL28426322

SCHEMBL28426322

BrC=CCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.58
DRD2 P14416 1/20 0.43
DRD4 P21917 1/20 0.43
DRD3 P35462 1/20 0.43
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
HTR7 P34969 1/20 0.35
HTR2B P41595 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOA P21397 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
GABRA1 P14867 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27918777 0.84 PNMT (0.58) PNMTDRD2DRD4DRD3NPC1
SCHEMBL10774995 0.84 PNMT (0.63) PNMTDRD2DRD4DRD3NPC1
SCHEMBL17186646 0.84 PNMT (0.58) PNMTDRD2DRD4DRD3NPC1
SCHEMBL1613258 0.81 PNMT (0.55) PNMTDRD2DRD4DRD3NPC1
SCHEMBL1613261 0.81 PNMT (0.55) PNMTDRD2DRD4DRD3NPC1
SCHEMBL123076 0.80 PNMT (0.62) PNMTDRD2DRD4DRD3NPC1
SCHEMBL252161 0.80 PNMT (0.62) PNMTDRD2DRD4DRD3NPC1
SCHEMBL28436107 0.79 PNMT (0.57) PNMTDRD2DRD4DRD3NPC1
Bromide SCHEMBL27762439 0.79 PNMT (0.60) PNMTDRD2DRD4DRD3NPC1
SCHEMBL5140756 0.78 PNMT (0.51) PNMTDRD2DRD4DRD3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109384908-B Polymer with main chain containing bromoalkylfluorene and application thereof in anion exchange membrane 浙江大学 2020-06-16 CN claimed
CN-112563520-B Homogeneous catalyst and catalyst layer of anion exchange membrane fuel cell 浙江大学 2021-11-02 CN disclosed
CN-112563520-A Homogeneous catalyst and catalyst layer of anion exchange membrane fuel cell 浙江大学 2021-03-26 CN disclosed
CN-109384908-B Polymer with main chain containing bromoalkylfluorene and application thereof in anion exchange membrane 浙江大学 2020-06-16 CN disclosed
CN-109384908-B Polymer with main chain containing bromoalkylfluorene and application thereof in anion exchange membrane 浙江大学 2020-06-16 CN disclosed
CN-109384908-B Polymer with main chain containing bromoalkylfluorene and application thereof in anion exchange membrane 浙江大学 2020-06-16 CN disclosed