SCHEMBL123076

SCHEMBL123076

O=CCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.62
DRD2 P14416 3/20 0.48
DRD4 P21917 3/20 0.48
DRD3 P35462 3/20 0.48
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
HTR7 P34969 1/20 0.40
HTR2B P41595 1/20 0.40
MAOA P21397 2/20 0.38
BCHE P06276 1/20 0.36
CES1 P23141 1/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
MAP3K9 P80192 1/20 0.34
MAP3K11 Q16584 1/20 0.34
MIF P14174 4/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15224289 0.85 PNMT (0.47) PNMTDRD2DRD4DRD3NPC1
SCHEMBL2328093 0.83 PNMT (0.58) PNMTDRD2DRD4DRD3NPC1
SCHEMBL252161 0.83 PNMT (0.62) PNMTDRD2DRD4DRD3NPC1
SCHEMBL27795073 0.82 PNMT (0.47) PNMTDRD2DRD4DRD3NPC1
SCHEMBL10775945 0.82 PNMT (0.57) PNMTDRD2DRD4DRD3NPC1
Bromide SCHEMBL27762439 0.81 PNMT (0.60) PNMTDRD2DRD4DRD3NPC1
SCHEMBL633763 0.80 PNMT (0.68) PNMTDRD2DRD4DRD3NPC1
SCHEMBL30606684 0.80 PNMT (0.68) PNMTDRD2DRD4DRD3NPC1
SCHEMBL263229 0.80 PNMT (0.68) PNMTDRD2DRD4DRD3NPC1
SCHEMBL4989855 0.80 PNMT (0.68) PNMTDRD2DRD4DRD3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1070 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084734-A Preparation method of O- [2- [ [ tert-butoxycarbonyl ] amino ] ethyl ] -N- [ fluorenylmethoxycarbonyl ] -L-tyrosine 成都海杰亚医药科技有限公司 2024-05-28 CN claimed
WO-2023183908-A1 TYK2 INHIBITOR SYNTHESIS AND INTERMEDIATES THEREOF NIMBUS LAKSHMI, INC. (US) 2023-09-28 WO claimed
CN-115611933-A Process for preparing arginase inhibitors and synthetic intermediates thereof 因赛特公司 2023-01-17 CN claimed
WO-2022016195-A1 PROCESSES FOR THE PREPARATION OF ARGINASE INHIBITORS AND THEIR SYNTHETIC INTERMEDIATES INCYTE CORPORATION (US) 2022-01-20 WO claimed
CN-109354600-B Preparation method of taurine modified novel Alaska cod multifunctional peptide 浙江海洋大学 2021-08-10 CN claimed
CN-109354600-A A kind of preparation method of the novel Alaska pollock multifunctional polypeptide of taurine modification 浙江海洋大学 2019-02-19 CN claimed
CN-104607163-B A kind of micro- chiral adjusting cellulose chromatography stationary phase, preparation method and applications 北京迪马欧泰科技发展中心 2018-05-15 CN claimed
WO-2013036684-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC (US) 2013-03-14 WO claimed
WO-2013036665-A1 COMPOUNDS FOR USE IN TREATING NEURODEGENERATIVE DISORDERS, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO SATORI PHARMACEUTICALS, INC. (US) 2013-03-14 WO claimed
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SATORI PHARMACEUTICALS, INC. (US) 2013-03-07 US claimed
US-20130060019-A1 Compounds for Use in Treating Neurodegenerative Disorders, Synthesis Thereof, and Intermediates Thereto SATORI PHARMACEUTICALS, INC. (US) 2013-03-07 US claimed
EP-2542085-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS Satori Pharmaceuticals, Inc. (US) 2013-01-09 EP claimed
US-20110251379-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC. (US) 2011-10-13 US claimed
WO-2011109657-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC. (US) 2011-09-09 WO claimed
EP-2283063-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS Intezyne Technologies Inc. (US) 2011-02-16 EP claimed
US-20090286938-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS INTEZYNE TECHNOLOGIES, INC. (US) 2009-11-19 US claimed
WO-2009134984-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS INTEZYNE TECHNOLGIES INC. (US) 2009-11-05 WO claimed
US-7612153-B2 conjugate polymer drugs; endcapped polyethers; nontoxic, biocompatible, non-immunogenic, soluble in water and other solvents INTEZYNE TECHNOLOGIES, INC. (US) 2009-11-03 US claimed
US-5608104-A QUICK ANALYSIS OF PYRETHROID COMPOUNDS WITH ANTIBODIES MITSUI TOATSU CHEMICALS, INC. (JP) 1997-03-04 US claimed
EP-0645628-A1 Immunological detection method of pyrethroid compound, haptenic compound, intermediate for the haptenic compound, immunogen and antibody MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-03-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286938-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS PFAS, GFPT1, PFKFB4 PNMT 1930/4885DRD2 3318/4885DRD4 1782/4885
US-20130060019-A1 Compounds for Use in Treating Neurodegenerative Disorders, Synthesis Thereof, and Intermediates Thereto SNCA, HTT, PARK7 PNMT 865/4885DRD2 2295/4885DRD4 2721/4885
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SNCA, HTT, CLN6 PNMT 452/4885DRD2 2308/4885DRD4 2059/4885
US-20110251379-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS CLN6, NLN, ACHE PNMT 50/4885DRD2 2388/4885DRD4 2088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.