Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79439 | 0.91 | S1PR1 (0.47) | S1PR1S1PR5PPARAPPARDKDM4E | |
| SCHEMBL2469794 | 0.82 | PKM (0.47) | S1PR1S1PR5RXRARXRBRXRG | |
| SCHEMBL16140749 | 0.79 | THRA (0.41) | PPARAPPARDKDM4EATM | |
| SCHEMBL2469798 | 0.78 | S1PR1 (0.37) | S1PR1S1PR5RXRARXRBRXRG | |
| SCHEMBL13851997 | 0.78 | S1PR1 (0.38) | S1PR1S1PR5PPARAPPARDKDM4E | |
| SCHEMBL2468566 | 0.77 | S1PR1 (0.70) | S1PR1S1PR5RXRARXRBRXRG | |
| SCHEMBL3493151 | 0.77 | S1PR1 (0.59) | S1PR1S1PR5RXRARXRBRXRG | |
| SCHEMBL86406 | 0.75 | S1PR1 (0.43) | S1PR1S1PR5RXRARXRBRXRG | |
| SCHEMBL13461833 | 0.74 | CTSS (0.49) | S1PR1KDM4EATM | |
| SCHEMBL31572513 | 0.74 | ROCK2 (0.43) | S1PR1S1PR5KDM4ETDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296183-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296183-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | HRH3, HRH2, HRH4 | S1PR1 370/4885S1PR5 463/4885RXRA 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.