SCHEMBL1614166

SCHEMBL1614166

C=C(Oc1ccccc1)C(=O)OCCOCCOCCO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
RECQL P46063 1/20 0.41
THRB P10828 2/20 0.39
SMN1; SMN2 Q16637 4/20 0.37
GAA P10253 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 2/20 0.36
CYP19A1 P11511 1/20 0.36
LMNA P02545 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
ELANE P08246 1/20 0.35
TSHR P16473 1/20 0.35
PTK2B Q14289 1/20 0.34
KDM4E B2RXH2 3/20 0.34
KCNH3 Q9ULD8 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181509 1.00 ALDH1A1 (0.41) ALDH1A1RECQLTHRBSMN1; SMN2GAA
SCHEMBL1835452 1.00 ALDH1A1 (0.41) ALDH1A1RECQLTHRBSMN1; SMN2GAA
SCHEMBL183505 1.00 ALDH1A1 (0.41) ALDH1A1RECQLTHRBSMN1; SMN2GAA
SCHEMBL517534 0.91 ALDH1A1 (0.46) ALDH1A1RECQLTHRBSMN1; SMN2GAA
SCHEMBL21357792 0.85 THRB (0.51) ALDH1A1THRBSMN1; SMN2KMT2AMEN1
Di(Hydroxyethyl)Ether SCHEMBL28640555 0.84 ALDH1A1 (0.46) ALDH1A1RECQLTHRBSMN1; SMN2GAA
SCHEMBL449722 0.80 LMNA (0.50) ALDH1A1THRBSMN1; SMN2GAAKMT2A
SCHEMBL6898989 0.79 RECQL (0.46) ALDH1A1RECQLTHRBSMN1; SMN2GAA
Diphenylether SCHEMBL2009809 0.79 THRB (0.49) ALDH1A1RECQLTHRBSMN1; SMN2NPC1
SCHEMBL2376423 0.78 SMN1; SMN2 (0.46) ALDH1A1RECQLSMN1; SMN2GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116925281-A Ophthalmic material and method for producing the same 爱博诺德(北京)医疗科技股份有限公司 2023-10-24 CN disclosed
CN-113024716-B Ophthalmic material and method for producing the same 爱博诺德(北京)医疗科技股份有限公司 2023-08-08 CN disclosed
CN-113021738-B Process for the preparation of ophthalmic materials 烟台爱博诺德医用材料有限公司 2023-06-27 CN disclosed
CN-110643296-B Adhesive sheet 赛登化学株式会社 2022-07-01 CN disclosed
CN-113024716-A Ophthalmic material and method for producing same 爱博诺德(北京)医疗科技股份有限公司 2021-06-25 CN disclosed
CN-113021738-A Method for producing ophthalmic material 爱博诺德(北京)医疗科技股份有限公司 2021-06-25 CN disclosed
CN-110643296-A Adhesive sheet 赛登化学株式会社 2020-01-03 CN disclosed
US-8178279-B2 Negative radiation-sensitive resin composition JSR CORPORATION (JP) 2012-05-15 US disclosed
US-20110086938-A1 NEGATIVE RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2011-04-14 US disclosed
US-20040079926-A1 Mixture of polymer and metal compound in solvent; applying to glass sheet NIPPON OIL CORPORATION (JP) 2004-04-29 US disclosed
EP-1363293-A1 IONICALLY CONDUCTING SHEET Nippon Oil Corporation (JP) 2003-11-19 EP disclosed